Background: There is concern about increasing utilization of low-value health care services, including preoperative testing for low-risk surgical procedures. We investigated temporal trends, ...

There is much recent interest in finding rare genetic variants associated with various diseases. Owing to the scarcity of rare mutations, single-variant analyses often lack power. To enable pooling of ...

WHEN OSHA's revised Respiratory Protection Standard for General Industry, 29 CFR 1910.134, became effective on April 8, 1998, it provided employers with an all-inclusive reference source for fit ...

The FDA expanded the marketing indications of a line of diagnostic tests to include checks for Lyme disease—the first cleared by the agency to use a new parallel testing method. Developed by Zeus ...

A total knee replacement (TKR) may sound like a pretty drastic operation, but in fact it is an increasingly routine process providing relief from pain, improved leg function and improved quality of ...

Tarone (1990, Biometrics 46, 515-522) proposed a multiple test procedure for discrete test statistics improving the usual Bonferroni procedure. However, Tarone's procedure is not monotone depending on ...